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CDK16 Phosphorylates and Degrades p53 to Promote Radioresistance and Predicts Prognosis in Lung Cancer

Rationale: Radioresistance is considered the main cause of local relapse in lung cancer. However, the molecular mechanisms of radioresistance remain poorly understood. This study investigates the role of CDK16 in radioresistance of human lung cancer cells. Methods: The expression levels of CDK16 wer...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Theranostics
Päätekijät: Xie, Jie, Li, Yan, Jiang, Ke, Hu, Kaishun, Zhang, Sheng, Dong, Xiaorong, Dai, Xiaofang, Liu, Li, Zhang, Tao, Yang, Kunyu, Huang, Kai, Chen, Junjie, Shi, Shaojun, Zhang, Yu, Wu, Gang, Xu, Shuangbing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ivyspring International Publisher 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771083/
https://ncbi.nlm.nih.gov/pubmed/29344296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.21963
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