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pKID Binds to KIX via an Unstructured Transition State with Nonnative Interactions

Understanding the detailed mechanism of interaction of intrinsically disordered proteins with their partners is crucial to comprehend their functions in signaling and transcription. Through its interaction with KIX, the disordered pKID region of CREB protein is central in the transcription of cAMP r...

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書目詳細資料
發表在:Biophys J
Main Authors: Dahal, Liza, Kwan, Tristan O.C., Shammas, Sarah L., Clarke, Jane
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770965/
https://ncbi.nlm.nih.gov/pubmed/29262364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.016
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