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pKID Binds to KIX via an Unstructured Transition State with Nonnative Interactions

Understanding the detailed mechanism of interaction of intrinsically disordered proteins with their partners is crucial to comprehend their functions in signaling and transcription. Through its interaction with KIX, the disordered pKID region of CREB protein is central in the transcription of cAMP r...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Dahal, Liza, Kwan, Tristan O.C., Shammas, Sarah L., Clarke, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770965/
https://ncbi.nlm.nih.gov/pubmed/29262364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.016
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