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Explicit Characterization of the Free Energy Landscape of pKID–KIX Coupled Folding and Binding

[Image: see text] The most fundamental aspect of the free energy landscape of proteins is that it is globally funneled such that protein folding is energetically biased. Then, what are the distinctive characteristics of the landscape of intrinsically disordered proteins, apparently lacking such ener...

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Pubblicato in:ACS Cent Sci
Autori principali: Chong, Song-Ho, Im, Haeri, Ham, Sihyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2019
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6716127/
https://ncbi.nlm.nih.gov/pubmed/31482116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b00200
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