Llwytho...

Control of RAB7 activity and localization through the retromer‐TBC1D5 complex enables RAB7‐dependent mitophagy

Retromer is an endosomal multi‐protein complex that organizes the endocytic recycling of a vast range of integral membrane proteins. Here, we establish an additional retromer function in controlling the activity and localization of the late endosomal small GTPase RAB7. Surprisingly, we found that RA...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Jimenez‐Orgaz, Ana, Kvainickas, Arunas, Nägele, Heike, Denner, Justin, Eimer, Stefan, Dengjel, Jörn, Steinberg, Florian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770787/
https://ncbi.nlm.nih.gov/pubmed/29158324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797128
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