Caricamento...

Control of RAB7 activity and localization through the retromer‐TBC1D5 complex enables RAB7‐dependent mitophagy

Retromer is an endosomal multi‐protein complex that organizes the endocytic recycling of a vast range of integral membrane proteins. Here, we establish an additional retromer function in controlling the activity and localization of the late endosomal small GTPase RAB7. Surprisingly, we found that RA...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Jimenez‐Orgaz, Ana, Kvainickas, Arunas, Nägele, Heike, Denner, Justin, Eimer, Stefan, Dengjel, Jörn, Steinberg, Florian
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770787/
https://ncbi.nlm.nih.gov/pubmed/29158324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797128
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !