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Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50
Retromer and the associated actin-polymerizing WASH complex are essential for the endocytic recycling of a wide range of integral membrane proteins. A hereditary Parkinson's-disease-causing point mutation (D620N) in the retromer subunit VPS35 perturbs retromer's association with the WASH c...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5278674/ https://ncbi.nlm.nih.gov/pubmed/27909246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.196758 |
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