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Inhibition of TBC1D5 activates Rab7a and can enhance the function of the retromer cargo-selective complex

The retromer complex is a vital component of the endosomal protein sorting machinery necessary for sorting into both the endosome-to-Golgi retrieval pathway and also the endosome-to-cell-surface recycling pathway. Retromer mediates cargo selection through a trimeric complex comprising VPS35, VPS29 a...

詳細記述

保存先:
書誌詳細
出版年:J Cell Sci
主要な著者: Seaman, Matthew N. J., Mukadam, Aamir S., Breusegem, Sophia Y.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists Ltd 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031384/
https://ncbi.nlm.nih.gov/pubmed/29777037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.217398
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