TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue

Remodelling of energy storing white fat into energy expending beige fat could be a promising strategy to reduce adiposity. Here, we show that the bile acid-responsive membrane receptor TGR5 mediates beiging of the subcutaneous white adipose tissue (scWAT) under multiple environmental cues including...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Velazquez-Villegas, Laura A., Perino, Alessia, Lemos, Vera, Zietak, Marika, Nomura, Mitsunori, Pols, Thijs Willem Hendrik, Schoonjans, Kristina
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770450/
https://ncbi.nlm.nih.gov/pubmed/29339725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02068-0
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