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TGR5 reduces macrophage migration through mTOR-induced C/EBPβ differential translation

The bile acid–responsive G protein–coupled receptor TGR5 is involved in several metabolic processes, and recent studies suggest that TGR5 activation may promote pathways that are protective against diet-induced diabetes. Here, we investigated the role of macrophage-specific TGR5 signaling in protect...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Perino, Alessia, Pols, Thijs Willem Hendrik, Nomura, Mitsunori, Stein, Sokrates, Pellicciari, Roberto, Schoonjans, Kristina
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348975/
https://ncbi.nlm.nih.gov/pubmed/25365223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76289
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