Amino acid substitutions affecting aspartic acid 605 and valine 606 decrease the interaction strength between the influenza virus RNA polymerase PB2 '627' domain and the viral nucleoprotein

The influenza virus RNA genome is transcribed and replicated in the context of the viral ribonucleoprotein (vRNP) complex by the viral RNA polymerase. The nucleoprotein (NP) is the structural component of the vRNP providing a scaffold for the viral RNA. In the vRNP as well as during transcription an...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Hsia, Ho-Pan, Yang, Yin-Hua, Szeto, Wun-Chung, Nilsson, Benjamin E., Lo, Chun-Yeung, Ng, Andy Ka-Leung, Fodor, Ervin, Shaw, Pang-Chui
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770049/
https://ncbi.nlm.nih.gov/pubmed/29338047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191226
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk