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In colonic ρ(0) (rho0) cells reduced mitochondrial function mediates transcriptomic alterations associated with cancer

BACKGROUND: Mitochondrial reprogramming has emerged as a hallmark of cancer pathobiology. Although it is believed this reprogramming is essential for cancer cells to thrive, how it supports cancer pathobiology is unclear. We previously generated colonic ρ0 (rho0) cells with reduced mitochondrial ene...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoscience
Hauptverfasser: Penrose, Harrison M., Heller, Sandra, Cable, Chloe, Nakhoul, Hani, Ungerleider, Nate, Baddoo, Melody, Pursell, Zachary F., Flemington, Erik K., Crawford, Susan E., Savkovic, Suzana D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769983/
https://ncbi.nlm.nih.gov/pubmed/29344557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.386
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