In colonic ρ(0) (rho0) cells reduced mitochondrial function mediates transcriptomic alterations associated with cancer

BACKGROUND: Mitochondrial reprogramming has emerged as a hallmark of cancer pathobiology. Although it is believed this reprogramming is essential for cancer cells to thrive, how it supports cancer pathobiology is unclear. We previously generated colonic ρ0 (rho0) cells with reduced mitochondrial ene...

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Detalhes bibliográficos
Publicado no:Oncoscience
Main Authors: Penrose, Harrison M., Heller, Sandra, Cable, Chloe, Nakhoul, Hani, Ungerleider, Nate, Baddoo, Melody, Pursell, Zachary F., Flemington, Erik K., Crawford, Susan E., Savkovic, Suzana D.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769983/
https://ncbi.nlm.nih.gov/pubmed/29344557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.386
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