Reduced mitochondrial activity in colonocytes facilitates AMPKα2-dependent inflammation

Intestinal inflammation is associated with low levels of mucosal ATP, highlighting the importance of mitochondrial function associated with ATP production in the pathophysiology of the disease. In the inflamed colon of humans and mice, we found decreased levels of mitochondrial complex cytochrome c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FASEB J
Prif Awduron: Heller, Sandra, Penrose, Harrison M., Cable, Chloe, Biswas, Debjani, Nakhoul, Hani, Baddoo, Melody, Flemington, Erik, Crawford, Susan E., Savkovic, Suzana D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Federation of American Societies for Experimental Biology 2017
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5388551/
https://ncbi.nlm.nih.gov/pubmed/28183804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600976R
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