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Reduced mitochondrial activity in colonocytes facilitates AMPKα2-dependent inflammation
Intestinal inflammation is associated with low levels of mucosal ATP, highlighting the importance of mitochondrial function associated with ATP production in the pathophysiology of the disease. In the inflamed colon of humans and mice, we found decreased levels of mitochondrial complex cytochrome c...
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Publicado no: | FASEB J |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Federation of American Societies for Experimental Biology
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5388551/ https://ncbi.nlm.nih.gov/pubmed/28183804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600976R |
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