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C3aR and C5aR1 act as key regulators of human and mouse β-cell function

AIMS: Complement components 3 and 5 (C3 and C5) play essential roles in the complement system, generating C3a and C5a peptides that are best known as chemotactic and inflammatory factors. In this study we characterised islet expression of C3 and C5 complement components, and the impact of C3aR and C...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Atanes, Patricio, Ruz-Maldonado, Inmaculada, Pingitore, Attilio, Hawkes, Ross, Liu, Bo, Zhao, Min, Huang, Guo Cai, Persaud, Shanta J., Amisten, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769825/
https://ncbi.nlm.nih.gov/pubmed/28921001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-017-2655-1
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