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C3aR and C5aR1 act as key regulators of human and mouse β-cell function

AIMS: Complement components 3 and 5 (C3 and C5) play essential roles in the complement system, generating C3a and C5a peptides that are best known as chemotactic and inflammatory factors. In this study we characterised islet expression of C3 and C5 complement components, and the impact of C3aR and C...

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Bibliografiska uppgifter
I publikationen:Cell Mol Life Sci
Huvudupphovsmän: Atanes, Patricio, Ruz-Maldonado, Inmaculada, Pingitore, Attilio, Hawkes, Ross, Liu, Bo, Zhao, Min, Huang, Guo Cai, Persaud, Shanta J., Amisten, Stefan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer International Publishing 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769825/
https://ncbi.nlm.nih.gov/pubmed/28921001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-017-2655-1
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