Streptococcus pneumoniae Attenuated Strain SPY1 with an Artificial Mineral Shell Induces Humoral and Th17 Cellular Immunity and Protects Mice against Pneumococcal Infection

Streptococcus pneumoniae is a major pathogen leading to substantial morbidity and mortality in children under 5 years of age. Vaccination is an effective strategy to prevent S. pneumoniae infection. SPY1 is a pneumococcal vaccine candidate strain obtained in our previous study. To improve its stabil...

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發表在:Front Immunol
Main Authors: Zhang, Xinyuan, Cui, Jingjing, Wu, Yingying, Wang, Hong, Wang, Jian, Qiu, Yulan, Mo, Yunjun, He, Yujuan, Zhang, Xuemei, Yin, Yibing, Xu, Wenchun
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768616/
https://ncbi.nlm.nih.gov/pubmed/29375585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01983
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