Streptococcus pneumoniae Attenuated Strain SPY1 with an Artificial Mineral Shell Induces Humoral and Th17 Cellular Immunity and Protects Mice against Pneumococcal Infection

Streptococcus pneumoniae is a major pathogen leading to substantial morbidity and mortality in children under 5 years of age. Vaccination is an effective strategy to prevent S. pneumoniae infection. SPY1 is a pneumococcal vaccine candidate strain obtained in our previous study. To improve its stabil...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Zhang, Xinyuan, Cui, Jingjing, Wu, Yingying, Wang, Hong, Wang, Jian, Qiu, Yulan, Mo, Yunjun, He, Yujuan, Zhang, Xuemei, Yin, Yibing, Xu, Wenchun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768616/
https://ncbi.nlm.nih.gov/pubmed/29375585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01983
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