Phylogenetic Distribution of CMP-Neu5Ac Hydroxylase (CMAH), the Enzyme Synthetizing the Proinflammatory Human Xenoantigen Neu5Gc

The enzyme CMP-N-acetylneuraminic acid hydroxylase (CMAH) is responsible for the synthesis of N-glycolylneuraminic acid (Neu5Gc), a sialic acid present on the cell surface proteins of most deuterostomes. The CMAH gene is thought to be present in most deuterostomes, but it has been inactivated in a n...

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Dettagli Bibliografici
Pubblicato in:Genome Biol Evol
Autori principali: Peri, Sateesh, Kulkarni, Asmita, Feyertag, Felix, Berninsone, Patricia M, Alvarez-Ponce, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767959/
https://ncbi.nlm.nih.gov/pubmed/29206915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evx251
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