Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs

After the knock-out (KO) of α1,3 galactosyltransfease (Gal-T), the Hanganutziu-Deicher antigen became a major antigen of the "non-Gal antigen" that is implicated in subsequent xenograft rejection. For deletion of non-Gal antigen, we successfully produced zinc finger nuclease (ZFN)-mediated...

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Main Authors: Kwon, Deug-Nam, Lee, Kiho, Kang, Man-Jong, Choi, Yun-Jung, Park, Chankyu, Whyte, Jeffrey J., Brown, Alana N., Kim, Jae-Hwan, Samuel, Melissa, Mao, Jiude, Park, Kwang-Wook, Murphy, Clifton N., Prather, Randall S., Kim, Jin-Hoi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070623/
https://ncbi.nlm.nih.gov/pubmed/23760311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01981
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