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Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs
After the knock-out (KO) of α1,3 galactosyltransfease (Gal-T), the Hanganutziu-Deicher antigen became a major antigen of the "non-Gal antigen" that is implicated in subsequent xenograft rejection. For deletion of non-Gal antigen, we successfully produced zinc finger nuclease (ZFN)-mediated...
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| Glavni autori: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4070623/ https://ncbi.nlm.nih.gov/pubmed/23760311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01981 |
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