Structure-Based Virtual Screening for the Discovery of Novel Inhibitors of New Delhi Metallo-β-lactamase-1

[Image: see text] Bacterial resistance has become a worldwide concern after the emergence of metallo-β-lactamases (MBLs). They represent one of the major mechanisms of bacterial resistance against beta-lactam antibiotics. Among MBLs, New Delhi metallo-β-lactamase-1 NDM-1, the most prevalent type, is...

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Bibliographic Details
Published in:ACS Med Chem Lett
Main Authors: Spyrakis, Francesca, Celenza, Giuseppe, Marcoccia, Francesca, Santucci, Matteo, Cross, Simon, Bellio, Pierangelo, Cendron, Laura, Perilli, Mariagrazia, Tondi, Donatella
Format: Artigo
Language:Inglês
Published: American Chemical Society 2017
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767890/
https://ncbi.nlm.nih.gov/pubmed/29348810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00428
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