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PXR: More Than Just a Master Xenobiotic Receptor

Pregnane X receptor (PXR) is a nuclear receptor considered to be a master xenobiotic receptor that coordinately regulates the expression of genes encoding drug-metabolizing enzymes and drug transporters to essentially detoxify and eliminate xenobiotics and endotoxins from the body. In the past sever...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Oladimeji, Peter O., Chen, Taosheng
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5767680/
https://ncbi.nlm.nih.gov/pubmed/29113993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.110155
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