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Preparation of Stable Amyloid β-Protein Oligomers of Defined Assembly Order
Oligomeric assemblies of the amyloid β-protein, Aβ, are thought to be the proximate neurotoxic agents in Alzheimer’s disease (AD). Oligomer formation is a complex process that produces a polydisperse population of metastable structures. For this reason, formal structure–activity correlations, both i...
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| Veröffentlicht in: | Methods Mol Biol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5767166/ https://ncbi.nlm.nih.gov/pubmed/22528081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-551-0_3 |
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