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Continuous flow reactor for production of stable amyloid protein oligomers

The predominant working hypothesis of Alzheimer's disease is that the proximate pathologic agents are oligomers of the amyloid β-protein (Aβ). “Oligomer” is an ill-defined term. Many different types of oligomers have been reported and they often exist in rapid equilibrium with monomers and high...

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Publicado en:Biochemistry
Autores principales: Hayden, Eric Yale, Teplow, David B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624790/
https://ncbi.nlm.nih.gov/pubmed/22803680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3007687
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