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The Sec61/SecY complex is inherently deficient in translocating intrinsically disordered proteins
About one-quarter to nearly one-third of the proteins synthesized in the cytosol of eukaryotic cells are integrated into the plasma membrane or are secreted. Translocation of secretory proteins into the lumen of the endoplasmic reticulum or the periplasm of bacteria is mediated by a highly conserved...
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| 發表在: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766967/ https://ncbi.nlm.nih.gov/pubmed/29084847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.788067 |
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