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Conformational changes in the di-domain structure of Arabidopsis phosphoethanolamine methyltransferase leads to active-site formation

Phosphocholine (pCho) is a precursor for phosphatidylcholine and osmoprotectants in plants. In plants, de novo synthesis of pCho relies on the phosphobase methylation pathway. Phosphoethanolamine methyltransferase (PMT) catalyzes the triple methylation of phosphoethanolamine (pEA) to pCho. The plant...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Lee, Soon Goo, Jez, Joseph M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766937/
https://ncbi.nlm.nih.gov/pubmed/29084845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000106
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