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Crystal structure of phosphoethanolamine methyltransferase from Plasmodium falciparum in complex with amodiaquine
Phosphoethanolamine N-methyltransferase (PMT) is essential for phospholipid biogenesis in the malarial parasite Plasmodium falciparum. PfPMT catalyzes the triple methylation of phosphoethanolamine to produce phosphocholine, which is then used for phosphatidylcholine synthesis. Here we describe the 2...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401361/ https://ncbi.nlm.nih.gov/pubmed/22771008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.06.032 |
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