An Alternative Mechanism for the Methylation of Phosphoethanolamine Catalyzed by Plasmodium falciparum Phosphoethanolamine Methyltransferase

The phosphobase methylation pathway catalyzed by the phosphoethanolamine methyltransferase in Plasmodium falciparum (PfPMT), the malaria parasite, offers an attractive target for anti-parasitic drug development. PfPMT methylates phosphoethanolamine (pEA) to phosphocholine for use in membrane biogene...

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Vydáno v:J Biol Chem
Hlavní autoři: Saen-oon, Suwipa, Lee, Soon Goo, Jez, Joseph M., Guallar, Victor
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256317/
https://ncbi.nlm.nih.gov/pubmed/25288796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.611319
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