Structure and Reaction Mechanism of Phosphoethanolamine Methyltransferase from the Malaria Parasite Plasmodium falciparum: AN ANTIPARASITIC DRUG TARGET

In the malarial parasite Plasmodium falciparum, a multifunctional phosphoethanolamine methyltransferase (PfPMT) catalyzes the methylation of phosphoethanolamine (pEA) to phosphocholine for membrane biogenesis. This pathway is also found in plant and nematodes, but PMT from these organisms use multip...

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Detalhes bibliográficos
Main Authors: Lee, Soon Goo, Kim, Youngchang, Alpert, Tara D., Nagata, Akina, Jez, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256908/
https://ncbi.nlm.nih.gov/pubmed/22117061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.315267
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