ロード中...
Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding
Domain-minimized insulin receptors (IRs) have enabled crystallographic analysis of insulin-bound “micro-receptors.” In such structures, the C-terminal segment of the insulin B chain inserts between conserved IR domains, unmasking an invariant receptor-binding surface that spans both insulin A and B...
保存先:
| 出版年: | J Biol Chem |
|---|---|
| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2018
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766920/ https://ncbi.nlm.nih.gov/pubmed/29114034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.808667 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|