ロード中...
Insulin Fibrillation and Protein Design: Topological Resistance of Single-Chain Analogs to Thermal Degradation with Application to a Pump Reservoir
Insulin is susceptible to thermal fibrillation, a misfolding process that leads to nonnative cross-b assembly analogous to pathological amyloid deposition. Pharmaceutical formulations are ordinarily protected from such degradation by sequestration of the susceptible monomer within native protein ass...
保存先:
| 主要な著者: | , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Diabetes Technology Society
2012
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380768/ https://ncbi.nlm.nih.gov/pubmed/22538136 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|