A carregar...

Pregnane X receptor promotes ethanol-induced hepatosteatosis in mice

The pregnane X receptor (PXR, NR1I2) is a xenobiotic-sensing nuclear receptor that modulates the metabolic response to drugs and toxic agents. Both PXR activation and deficiency promote hepatic triglyceride accumulation, a hallmark feature of alcoholic liver disease. However, the molecular mechanism...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Choi, Sora, Neequaye, Prince, French, Samuel W., Gonzalez, Frank J., Gyamfi, Maxwell A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766906/
https://ncbi.nlm.nih.gov/pubmed/29123032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.815217
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!