Загрузка...
Pregnane X receptor promotes ethanol-induced hepatosteatosis in mice
The pregnane X receptor (PXR, NR1I2) is a xenobiotic-sensing nuclear receptor that modulates the metabolic response to drugs and toxic agents. Both PXR activation and deficiency promote hepatic triglyceride accumulation, a hallmark feature of alcoholic liver disease. However, the molecular mechanism...
Сохранить в:
| Опубликовано в: : | J Biol Chem |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2018
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766906/ https://ncbi.nlm.nih.gov/pubmed/29123032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.815217 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|