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Role of human pregnane X receptor in high fat diet-induced obesity in pre-menopausal female mice

Obesity is a complex metabolic disorder that is more prevalent among women. Until now, the only relevant rodent models of diet-induced obesity were via the use of ovariectomized (“postmenopausal”) females. However, recent reports suggest that the xenobiotic nuclear receptor pregnane X receptor (PXR)...

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Detalhes bibliográficos
Main Authors: Spruiell, Krisstonia, Jones, Dominique Z., Cullen, John M., Awumey, Emmanuel M., Gonzalez, Frank J., Gyamfi, Maxwell A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057797/
https://ncbi.nlm.nih.gov/pubmed/24721462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.03.019
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