Nudt21 controls cell fate by connecting alternative polyadenylation to chromatin signaling

Cell fate transitions involve rapid gene expression changes and global chromatin remodeling, yet the underlying regulatory pathways remain incompletely understood. Here, we identified the RNA-processing factor Nudt21 as a novel regulator of cell fate change using transcription factor induced reprogr...

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Bibliografske podrobnosti
izdano v:Cell
Main Authors: Brumbaugh, Justin, Di Stefano, Bruno, Wang, Xiuye, Borkent, Marti, Forouzmand, Elmira, Clowers, Katie J., Ji, Fei, Schwarz, Benjamin A., Kalocsay, Marian, Elledge, Stephen J., Chen, Yue, Sadreyev, Ruslan I., Gygi, Steven P., Hu, Guang, Shi, Yongsheng, Hochedlinger, Konrad
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766360/
https://ncbi.nlm.nih.gov/pubmed/29249356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.11.023
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