Protein kinase- and lipase inhibitors of inositide metabolism deplete IP(7) indirectly in pancreatic β-cells: Off-target effects on cellular bioenergetics and direct effects on IP6K activity

Inositol pyrophosphates have emerged as important regulators of many critical cellular processes from vesicle trafficking and cytoskeletal rearrangement to telomere length regulation and apoptosis. We have previously demonstrated that 5-di-phosphoinositol pentakisphosphate, IP(7), is at a high level...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Signal
Main Authors: Rajasekaran, Subu Surendran, Illies, Christopher, Shears, Stephen B., Wang, Huanchen, Ayala, Thais S., Martins, Joilson O., Daré, Elisabetta, Berggren, Per-Olof, Barker, Christopher J.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Science Ltd 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765549/
https://ncbi.nlm.nih.gov/pubmed/29042286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2017.10.008
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki