Inositol hexakisphosphate kinase 1 is a metabolic sensor in pancreatic β-cells

Diphosphoinositol pentakisphosphate (IP(7)) is critical for the exocytotic capacity of the pancreatic β-cell, but its regulation by the primary instigator of β-cell exocytosis, glucose, is unknown. The high K(m) for ATP of the IP(7)-generating enzymes, the inositol hexakisphosphate kinases (IP6K1 an...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Signal
Egile Nagusiak: Rajasekaran, Subu Surendran, Kim, Jaeyoon, Gaboardi, Gian-Carlo, Gromada, Jesper, Shears, Stephen B., dos Santos, Karen Tiago, Nolasco, Eduardo Lima, Ferreira, Sabrina de Souza, Illies, Christopher, Köhler, Martin, Gu, Chunfang, Ryu, Sung Ho, Martins, Joilson O., Darè, Elisabetta, Barker, Christopher J., Berggren, Per-Olof
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier Science Ltd 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899964/
https://ncbi.nlm.nih.gov/pubmed/29522819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.03.001
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