Mass Spectrometric Analysis of Cerebrospinal Fluid Ubiquitin in Alzheimer's Disease and Parkinsonian Disorders

PURPOSE: Dysfunctional proteostasis, with decreased protein degradation and an accumulation of ubiquitin into aggregated protein inclusions, is a feature of neurodegenerative diseases. Identifying new potential biomarkers in cerebrospinal fluid (CSF) reflecting this process could contribute importan...

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Bibliografiske detaljer
Udgivet i:Proteomics Clin Appl
Main Authors: Sjödin, Simon, Hansson, Oskar, Öhrfelt, Annika, Brinkmalm, Gunnar, Zetterberg, Henrik, Brinkmalm, Ann, Blennow, Kaj
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765402/
https://ncbi.nlm.nih.gov/pubmed/28972305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.201700100
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