SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer’s disease

BACKGROUND: Synaptic degeneration is an early pathogenic event in Alzheimer’s disease, associated with cognitive impairment and disease progression. Cerebrospinal fluid biomarkers reflecting synaptic integrity would be highly valuable tools to monitor synaptic degeneration directly in patients. We p...

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Vydáno v:Mol Neurodegener
Hlavní autoři: Brinkmalm, Ann, Brinkmalm, Gunnar, Honer, William G, Frölich, Lutz, Hausner, Lucrezia, Minthon, Lennart, Hansson, Oskar, Wallin, Anders, Zetterberg, Henrik, Blennow, Kaj, Öhrfelt, Annika
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253625/
https://ncbi.nlm.nih.gov/pubmed/25418885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-53
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