SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer’s disease

BACKGROUND: Synaptic degeneration is an early pathogenic event in Alzheimer’s disease, associated with cognitive impairment and disease progression. Cerebrospinal fluid biomarkers reflecting synaptic integrity would be highly valuable tools to monitor synaptic degeneration directly in patients. We p...

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Publicat a:Mol Neurodegener
Autors principals: Brinkmalm, Ann, Brinkmalm, Gunnar, Honer, William G, Frölich, Lutz, Hausner, Lucrezia, Minthon, Lennart, Hansson, Oskar, Wallin, Anders, Zetterberg, Henrik, Blennow, Kaj, Öhrfelt, Annika
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253625/
https://ncbi.nlm.nih.gov/pubmed/25418885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-53
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