Increased Cerebrospinal Fluid Levels of Ubiquitin Carboxyl-Terminal Hydrolase L1 in Patients with Alzheimer's Disease

BACKGROUND: Dysfunctions of the ubiquitin proteasome system (UPS), including the highly abundant neuronal enzyme ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1), and autophagy-related changes (lysosomal degradation) are implicated in several neurodegenerative disorders including Alzheimer's d...

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Vydáno v:Dement Geriatr Cogn Dis Extra
Hlavní autoři: Öhrfelt, Annika, Johansson, Per, Wallin, Anders, Andreasson, Ulf, Zetterberg, Henrik, Blennow, Kaj, Svensson, Johan
Médium: Artigo
Jazyk:Inglês
Vydáno: S. Karger AG 2016
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Original Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965532/
https://ncbi.nlm.nih.gov/pubmed/27504117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000447239
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