Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) S18Y polymorphism in Alzheimer's disease

Alzheimer's disease (AD) is characterized by protein aggregates, i.e. senile plaques and neurofibrillary tangles. The ubiquitin-proteasome system has been proposed a role in proteolytic removal of these protein aggregates. Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) is a de-ubiquitinating e...

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Detalhes bibliográficos
Main Authors: Zetterberg, Madeleine, Sjölander, Annica, von Otter, Malin, Palmér, Mona Seibt, Landgren, Sara, Minthon, Lennart, Wallin, Anders, Andreasen, Niels, Blennow, Kaj, Zetterberg, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848225/
https://ncbi.nlm.nih.gov/pubmed/20302621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-11
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