Dual inhibition of the mTORC1 and mTORC2 signaling pathways is a promising therapeutic target for adult T‐cell leukemia

Adult T‐cell leukemia (ATL) has a poor prognosis as a result of severe immunosuppression and rapid tumor progression with resistance to conventional chemotherapy. Recent integrated‐genome analysis has revealed mutations in many genes involved in the T‐cell signaling pathway, suggesting that the aber...

Full description

Saved in:
Bibliographic Details
Published in:Cancer Sci
Main Authors: Kawata, Takahito, Tada, Kohei, Kobayashi, Masayuki, Sakamoto, Takashi, Takiuchi, Yoko, Iwai, Fumie, Sakurada, Maki, Hishizawa, Masakatsu, Shirakawa, Kotaro, Shindo, Keisuke, Sato, Hironori, Takaori‐Kondo, Akifumi
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
Subjects:
Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765289/
https://ncbi.nlm.nih.gov/pubmed/29077243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13431
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items