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Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury
Excessive fatty acid release from the white adipose tissue (WAT) contributes to the development of alcoholic liver disease (ALD). Lipin1 (LPIN1), as a co-regulator of DNA-bound transcription factors and a phosphatidic acid (PA) phosphatase (PAP) enzyme that dephosphorylates PA to form diacylglycerol...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5765113/ https://ncbi.nlm.nih.gov/pubmed/29323242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18837-2 |
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