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Pharmacological inhibition of NOX4 ameliorates alcohol-induced liver injury in mice through improving oxidative stress and mitochondrial function

BACKGROUND: Oxidative stress plays a crucial role in the development of alcoholic liver disease (ALD), however effective pharmacological treatments for oxidative injury is still lacking. The objective of this study was to determine whether inhibition of NADPH oxidase activity could reverse alcohol-i...

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Dades bibliogràfiques
Publicat a:Biochim Biophys Acta
Autors principals: Sun, Qian, Zhang, Wenliang, Zhong, Wei, Sun, Xinguo, Zhou, Zhanxiang
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742866/
https://ncbi.nlm.nih.gov/pubmed/27634671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2016.09.009
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