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Downregulation of Heat Shock Protein 70 Impairs Osteogenic and Chondrogenic Differentiation in Human Mesenchymal Stem Cells

Human mesenchymal stem cells (hMSCs) show promise for bone and cartilage regeneration. Our previous studies demonstrated that hMSCs with periodic mild heating had enhanced osteogenic and chondrogenic differentiation with significantly upregulated heat shock protein 70 (HSP70). However, the role of H...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Li, Chenghai, Sunderic, Kristifor, Nicoll, Steven B., Wang, Sihong
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765044/
https://ncbi.nlm.nih.gov/pubmed/29323151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18541-1
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