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Downregulation of Heat Shock Protein 70 Impairs Osteogenic and Chondrogenic Differentiation in Human Mesenchymal Stem Cells

Human mesenchymal stem cells (hMSCs) show promise for bone and cartilage regeneration. Our previous studies demonstrated that hMSCs with periodic mild heating had enhanced osteogenic and chondrogenic differentiation with significantly upregulated heat shock protein 70 (HSP70). However, the role of H...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Li, Chenghai, Sunderic, Kristifor, Nicoll, Steven B., Wang, Sihong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765044/
https://ncbi.nlm.nih.gov/pubmed/29323151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18541-1
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