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Downregulation of Heat Shock Protein 70 Impairs Osteogenic and Chondrogenic Differentiation in Human Mesenchymal Stem Cells

Human mesenchymal stem cells (hMSCs) show promise for bone and cartilage regeneration. Our previous studies demonstrated that hMSCs with periodic mild heating had enhanced osteogenic and chondrogenic differentiation with significantly upregulated heat shock protein 70 (HSP70). However, the role of H...

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Pubblicato in:Sci Rep
Autori principali: Li, Chenghai, Sunderic, Kristifor, Nicoll, Steven B., Wang, Sihong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765044/
https://ncbi.nlm.nih.gov/pubmed/29323151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18541-1
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