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Downregulation of Heat Shock Protein 70 Impairs Osteogenic and Chondrogenic Differentiation in Human Mesenchymal Stem Cells

Human mesenchymal stem cells (hMSCs) show promise for bone and cartilage regeneration. Our previous studies demonstrated that hMSCs with periodic mild heating had enhanced osteogenic and chondrogenic differentiation with significantly upregulated heat shock protein 70 (HSP70). However, the role of H...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Li, Chenghai, Sunderic, Kristifor, Nicoll, Steven B., Wang, Sihong
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765044/
https://ncbi.nlm.nih.gov/pubmed/29323151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18541-1
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